Angela Anderson is a fourth year graduate student in the Human Nutrition, Foods and Exercise department at Virginia Tech.
She is a graduate of Pacific Lutheran University in Tacoma, Washington earning a Bachelors in Biology and Psychology, with a Chemistry minor.
Her current research is in ovarian cancer metabolism. As cancer progresses, cells make a metabolic shift from oxidative phosphorylation to a glycolytic phenotype. Using a mouse ovarian surface epithelial (MOSE) cell line that was developed by her advisor, Dr. Schmelz, she has characterized this metabolic shift and has used a chemotherapeutic agent, sphingosine, to analyze the reversal of this metabolic shift. Her next project will be incubating these cells in an immune cell environment and observing metabolic changes. Cancer cells are able to evade the immune system, but does the immune system affect cancer cells?
Angela’s initial work with the MOSE cells was presented at the American Association for Cancer Research (AACR) conference in Orlando, Florida in April 2011. Later that month she presented her research at the Virginia Tech Cancer Symposium. She has also collaborated with Dr. Hulver’s lab in research looking at metabolic changes seen in TLR-4 overexpressing mice. This work was presented at the American Diabetic Association conference in San Diego, CA in June 2011.
Angela is in her second year as a teaching assistant for Metabolic Nutrition. She teaches two sections of recitation a week and guest lectures when needed.
Angela received the Mike Houston Memorial Scholarship in April 2011, awarded for her excellence as a teaching assistant.